Listar por autor "Sáez Castresana, Javier"
Mostrando ítems 1-2 de 2
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Detection of methylation in promoter sequences by melting curve analysis-based semiquantitative real time PCR
Lorente, Aiala; Mueller, Wolf; Urdangarín, Edurne; Lázcoz, Paula
; Deimling, Andreas von; Sáez Castresana, Javier (BioMed Central, 2008)
Artículo / Artikulua 
Background: We present two melting curve analysis (MCA)-based semiquantitative real time PCR techniques to detect the promoter methylation status of genes. The first, MCA-MSP, follows the same principle as standard MSP ... -
Frequent promoter hypermethylation of RASSF1A and CASP8 in neuroblastoma
Lázcoz, Paula; Muñoz, Jorge; Nistal, Manuel; Pestaña, Ángel; Encío Martínez, Ignacio 
; Sáez Castresana, Javier (BioMed Central, 2006)
Artículo / Artikulua
Background: Epigenetic alterations and loss of heterozygosity are mechanisms of tumor suppressor gene inactivation. A new carcinogenic pathway, targeting the RAS effectors has recently been documented. RASSF1A, on 3p21.3, ...
